Are there nonstop flights from Knoxville/Maryville (TYS) to Tokyo (HND)?

No. The fastest connection is via Minneapolis, about 13h 48m of total flying time.

What is the fastest connection from Knoxville/Maryville (TYS) to Tokyo (HND)?

via Minneapolis ≈ 13h 48m, via Chicago ≈ 13h 49m, via Detroit ≈ 13h 58m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 40,000 JAL miles (economy, one way, based on the published award charts).

McGhee Tyson Airport (TYS) to Tokyo Haneda International Airport (HND)・10,878 km

No nonstop flights. The fastest connection is via Minneapolis (MSP), about 13h 48m of flying time (layover not included).

With milesANA 27,500 miles+ (via ORD)JAL 40,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

8 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.