Are there nonstop flights from San Diego (SAN) to Santiago (SCL)?

No. The fastest connection is via Los Angeles, about 11h 46m of total flying time.

What is the fastest connection from San Diego (SAN) to Santiago (SCL)?

via Los Angeles ≈ 11h 46m, via Panama City ≈ 12h 10m, via Houston ≈ 12h 18m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 40,000 JAL miles (economy, one way, based on the published award charts).

San Diego International Airport (SAN) to Comodoro Arturo Merino Benítez International Airport (SCL)・8,811 km

No nonstop flights. The fastest connection is via Los Angeles (LAX), about 11h 46m of flying time (layover not included).

With milesANA 30,000 miles+ (via PTY)JAL 40,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

10 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.