Are there nonstop flights from New York (JFK) to Santiago (SCL)?

Yes. LATAM Airlines Chile fly this route. Flight time is about 10h 12m.

What is the fastest connection from New York (JFK) to Santiago (SCL)?

via Bogota ≈ 10h 42m, via Cartagena ≈ 10h 43m, via Medellín ≈ 10h 43m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

John F. Kennedy International Airport (JFK) to Comodoro Arturo Merino Benítez International Airport (SCL)・8,238 km

Nonstop flights available (1 airline). Flight time about 10h 12m. Nonstop return flights also operate.

With milesANA 30,000 miles+ (via BOG)JAL 37,000 miles+ (via MIA)Economy, one way, estimate. Tap a connection for miles by cabin.

21 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.