Are there nonstop flights from Siem Reap (SAI) to Penang (PEN)?

No. The fastest connection is via Phnom Penh, about 2h 17m of total flying time.

What is the fastest connection from Siem Reap (SAI) to Penang (PEN)?

via Phnom Penh ≈ 2h 17m, via Phuket ≈ 2h 28m, via Bangkok ≈ 2h 33m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Siem Reap-Angkor International Airport (SAI) to Penang International Airport (PEN)・997 km

No nonstop flights. The fastest connection is via Phnom Penh (KTI), about 2h 17m of flying time (layover not included).

With milesANA 15,000 miles+ (via BKK)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

7 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.