Are there nonstop flights from Siem Reap (SAI) to Kuala Lumpur (KUL)?

Yes. AirAsia Cambodia fly this route. Flight time is about 1h 56m.

What is the fastest connection from Siem Reap (SAI) to Kuala Lumpur (KUL)?

via Preah Sihanouk ≈ 2h 25m, via Phu Quoc Island ≈ 2h 26m, via Phnom Penh ≈ 2h 29m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Siem Reap-Angkor International Airport (SAI) to Kuala Lumpur International Airport (KUL)・1,213 km

Nonstop flights available (1 airline). Flight time about 1h 56m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via BKK)Economy, one way, estimate. Tap a connection for miles by cabin.

9 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.