Are there nonstop flights from Puerto Plata (POP) to Holguin (HOG)?

No. The fastest connection is via Santo Domingo, about 2h 5m of total flying time.

What is the fastest connection from Puerto Plata (POP) to Holguin (HOG)?

via Santo Domingo ≈ 2h 5m (estimated flying time, excluding layovers).

Gregorio Luperon International Airport (POP) to Frank Pais International Airport (HOG)・610 km

No nonstop flights. The fastest connection is via Santo Domingo (SDQ), about 2h 5m of flying time (layover not included).

None.

1 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.