Are there nonstop flights from Chicago (ORD) to Santa Cruz (VVI)?

No. The fastest connection is via Miami, about 9h 21m of total flying time.

What is the fastest connection from Chicago (ORD) to Santa Cruz (VVI)?

via Miami ≈ 9h 21m, via Bogota ≈ 9h 23m, via Panama City ≈ 9h 30m (estimated flying time, excluding layovers).

from 30,000 ANA miles (economy, one way, based on the published award charts).

Chicago O'Hare International Airport (ORD) to Viru Viru International Airport (VVI)・7,101 km

No nonstop flights. The fastest connection is via Miami (MIA), about 9h 21m of flying time (layover not included).

With milesANA 30,000 miles+ (via BOG)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

5 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.