Are there nonstop flights from Mexico City (MEX) to Cartagena (CTG)?

Yes. Aeroméxico fly this route. Flight time is about 3h 42m.

What is the fastest connection from Mexico City (MEX) to Cartagena (CTG)?

via Panama City ≈ 4h 22m, via San José ≈ 4h 22m, via Medellín ≈ 5h 2m (estimated flying time, excluding layovers).

from 23,000 JAL miles, from 30,000 ANA miles (economy, one way, based on the published award charts).

Mexico City Benito Juárez International Airport (MEX) to Rafael Nuñez International Airport (CTG)・2,717 km

Nonstop flights available (1 airline). Flight time about 3h 42m. Nonstop return flights also operate.

With milesJAL 23,000 miles+ (via MIA)ANA 30,000 miles+ (via PTY)Economy, one way, estimate. Tap a connection for miles by cabin.

9 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.