Are there nonstop flights from Osaka (KIX) to Macau (MFM)?

Yes. Air Macau fly this route. Flight time is about 3h 27m.

What is the fastest connection from Osaka (KIX) to Macau (MFM)?

via Xiamen ≈ 3h 58m, via Fukuoka ≈ 3h 59m, via Taipei ≈ 4h (estimated flying time, excluding layovers).

from 11,500 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Kansai International Airport (KIX) to Macau International Airport (MFM)・2,513 km

Nonstop flights available (1 airline). Flight time about 3h 27m. Nonstop return flights also operate.

With milesANA 11,500 miles+ (via TPE)JAL 15,000 miles+ (via PVG)Economy, one way, estimate. Tap a connection for miles by cabin.

19 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.