Are there nonstop flights from Johannesburg (JNB) to Chicago (ORD)?

No. The fastest connection is via Newark, about 17h 29m of total flying time.

What is the fastest connection from Johannesburg (JNB) to Chicago (ORD)?

via Newark ≈ 17h 29m, via Atlanta ≈ 18h 8m, via Madrid ≈ 18h 28m (estimated flying time, excluding layovers).

from 35,000 ANA miles, from 47,000 JAL miles (economy, one way, based on the published award charts).

O.R. Tambo International Airport (JNB) to Chicago O'Hare International Airport (ORD)・14,019 km

No nonstop flights. The fastest connection is via Newark (EWR), about 17h 29m of flying time (layover not included).

With milesANA 35,000 miles+ (via EWR)JAL 47,000 miles+ (via CDG)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

17 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.