Are there nonstop flights from Newark (EWR) to Santiago (SCL)?

No. The fastest connection is via Bogota, about 10h 42m of total flying time.

What is the fastest connection from Newark (EWR) to Santiago (SCL)?

via Bogota ≈ 10h 42m, via Punta Cana ≈ 10h 46m, via Lima ≈ 10h 48m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Newark Liberty International Airport (EWR) to Comodoro Arturo Merino Benítez International Airport (SCL)・8,245 km

No nonstop flights. The fastest connection is via Bogota (BOG), about 10h 42m of flying time (layover not included).

With milesANA 30,000 miles+ (via BOG)JAL 37,000 miles+ (via MIA)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

16 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.