Are there nonstop flights from Newark (EWR) to Guadalajara (GDL)?

Yes. Volaris fly this route. Flight time is about 4h 41m.

What is the fastest connection from Newark (EWR) to Guadalajara (GDL)?

via Washington ≈ 5h 10m, via Atlanta ≈ 5h 12m, via Houston ≈ 5h 12m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 23,000 JAL miles (economy, one way, based on the published award charts).

Newark Liberty International Airport (EWR) to Guadalajara International Airport (GDL)・3,549 km

Nonstop flights available (1 airline). Flight time about 4h 41m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via IAH)JAL 23,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

33 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.