Are there nonstop flights from Charlotte (CLT) to Guadalajara (GDL)?

Yes. Volaris fly this route. Flight time is about 3h 43m.

What is the fastest connection from Charlotte (CLT) to Guadalajara (GDL)?

via Atlanta ≈ 4h 13m, via Houston ≈ 4h 17m, via San Antonio ≈ 4h 23m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Charlotte Douglas International Airport (CLT) to Guadalajara International Airport (GDL)・2,728 km

Nonstop flights available (1 airline). Flight time about 3h 43m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via IAH)JAL 15,000 miles+ (via DFW)Economy, one way, estimate. Tap a connection for miles by cabin.

26 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.