Are there nonstop flights from Newark (EWR) to Columbia (CAE)?

Yes. United Express fly this route. Flight time is about 1h 38m.

What is the fastest connection from Newark (EWR) to Columbia (CAE)?

via Washington ≈ 2h 9m, via Washington ≈ 2h 10m, via Charlotte ≈ 2h 10m (estimated flying time, excluding layovers).

Newark Liberty International Airport (EWR) to Columbia Metropolitan Airport (CAE)・970 km

Nonstop flights available (1 airline). Flight time about 1h 38m. Nonstop return flights also operate.

5 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.