Are there nonstop flights from Dushanbe (DYU) to Mashhad (MHD)?

Yes. Varesh Airlines, Raimon Airways fly this route. Flight time is about 1h 30m.

Dushanbe → Mashhad

Dushanbe International Airport (DYU) to Mashhad International Airport (MHD)・850 km

Nonstop flights available (2 airlines). Flight time about 1h 30m. Nonstop return flights also operate.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.