Are there nonstop flights from Des Moines (DSM) to Valparaiso (VPS)?

Yes. Allegiant Air fly this route. Flight time is about 2h 8m.

What is the fastest connection from Des Moines (DSM) to Valparaiso (VPS)?

via Nashville ≈ 2h 44m, via Atlanta ≈ 2h 52m, via Chicago ≈ 3h 4m (estimated flying time, excluding layovers).

from 15,000 JAL miles (economy, one way, based on the published award charts).

Des Moines International Airport (DSM) to Destin-Fort Walton Beach Airport (VPS)・1,385 km

Nonstop flights available (1 airline). Flight time about 2h 8m. Nonstop return flights also operate.

With milesJAL 15,000 miles+ (via ORD)Economy, one way, estimate. Tap a connection for miles by cabin.

14 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.