Are there nonstop flights from Des Moines (DSM) to London (LGW)?

No. The fastest connection is via Boston, about 9h 24m of total flying time.

What is the fastest connection from Des Moines (DSM) to London (LGW)?

via Boston ≈ 9h 24m, via Orlando ≈ 11h 24m (estimated flying time, excluding layovers).

Des Moines International Airport (DSM) to London Gatwick Airport (LGW)・6,760 km

No nonstop flights. The fastest connection is via Boston (BOS), about 9h 24m of flying time (layover not included).

None.

2 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.