Are there nonstop flights from Lanzarote (ACE) to Prague (PRG)?

Yes. Eurowings, Smartwings fly this route. Flight time is about 4h 24m.

What is the fastest connection from Lanzarote (ACE) to Prague (PRG)?

via Zurich ≈ 4h 54m, via Lyon ≈ 4h 54m, via Geneva ≈ 4h 54m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 23,000 JAL miles (economy, one way, based on the published award charts).

César Manrique-Lanzarote Airport (ACE) to Václav Havel Airport Prague (PRG)・3,317 km

Nonstop flights available (2 airlines). Flight time about 4h 24m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via BRU)JAL 23,000 miles+ (via HEL)Economy, one way, estimate. Tap a connection for miles by cabin.

58 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.