Are there nonstop flights from Valencia (VLC) to Prague (PRG)?

Yes. Eurowings, Smartwings fly this route. Flight time is about 2h 27m.

What is the fastest connection from Valencia (VLC) to Prague (PRG)?

via Munich ≈ 2h 57m, via Barcelona ≈ 2h 57m, via Marseille ≈ 2h 57m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Valencia Airport (VLC) to Václav Havel Airport Prague (PRG)・1,651 km

Nonstop flights available (2 airlines). Flight time about 2h 27m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via MUC)JAL 15,000 miles+ (via CDG)Economy, one way, estimate. Tap a connection for miles by cabin.

78 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.