Are there nonstop flights from Zakynthos (ZTH) to San Francisco (SFO)?

No. The fastest connection is via Munich, about 13h 44m of total flying time.

What is the fastest connection from Zakynthos (ZTH) to San Francisco (SFO)?

via Munich ≈ 13h 44m, via Amsterdam ≈ 13h 44m, via Frankfurt am Main ≈ 13h 45m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 45,000 JAL miles (economy, one way, based on the published award charts).

Zakynthos International Airport "Dionysios Solomos" (ZTH) to San Francisco International Airport (SFO)・10,826 km

No nonstop flights. The fastest connection is via Munich (MUC), about 13h 44m of flying time (layover not included).

With milesANA 27,500 miles+ (via WAW)JAL 45,000 miles+ (via LHR)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

10 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.