Are there nonstop flights from Zakynthos (ZTH) to Prague (PRG)?

Yes. Smartwings fly this route. Flight time is about 2h 14m.

What is the fastest connection from Zakynthos (ZTH) to Prague (PRG)?

via Corfu ≈ 2h 44m, via Kefallinia Island ≈ 2h 44m, via Preveza ≈ 2h 44m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 23,000 JAL miles (economy, one way, based on the published award charts).

Zakynthos International Airport "Dionysios Solomos" (ZTH) to Václav Havel Airport Prague (PRG)・1,471 km

Nonstop flights available (1 airline). Flight time about 2h 14m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via VIE)JAL 23,000 miles+ (via LHR)Economy, one way, estimate. Tap a connection for miles by cabin.

41 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.