Are there nonstop flights from Toronto (YYZ) to Harrisburg (MDT)?

No. The fastest connection is via Philadelphia, about 1h 48m of total flying time.

What is the fastest connection from Toronto (YYZ) to Harrisburg (MDT)?

via Philadelphia ≈ 1h 48m, via Washington ≈ 1h 50m, via Detroit ≈ 2h 6m (estimated flying time, excluding layovers).

Toronto Pearson International Airport (YYZ) to Harrisburg International Airport (MDT)・454 km

No nonstop flights. The fastest connection is via Philadelphia (PHL), about 1h 48m of flying time (layover not included).

None.

4 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.