Are there nonstop flights from Toronto (YYZ) to Medellín (MDE)?

Yes. Air Transat fly this route. Flight time is about 5h 26m.

What is the fastest connection from Toronto (YYZ) to Medellín (MDE)?

via Cartagena ≈ 5h 56m, via Montego Bay ≈ 5h 57m, via Fort Lauderdale ≈ 5h 58m (estimated flying time, excluding layovers).

from 23,000 JAL miles, from 30,000 ANA miles (economy, one way, based on the published award charts).

Toronto Pearson International Airport (YYZ) to Jose Maria Córdova International Airport (MDE)・4,191 km

Nonstop flights available (1 airline). Flight time about 5h 26m. Nonstop return flights also operate.

With milesJAL 23,000 miles+ (via MIA)ANA 30,000 miles+ (via CTG)Economy, one way, estimate. Tap a connection for miles by cabin.

20 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.