Are there nonstop flights from Toronto (YYZ) to Detroit (DTW)?

Yes. Delta Connection, Air Canada Express fly this route. Flight time is about 54m.

What is the fastest connection from Toronto (YYZ) to Detroit (DTW)?

via Cleveland ≈ 1h 33m, via Pittsburgh ≈ 1h 48m, via Columbus ≈ 1h 53m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Toronto Pearson International Airport (YYZ) to Detroit Metropolitan Wayne County Airport (DTW)・344 km

Nonstop flights available (2 airlines). Flight time about 54m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via ORD)Economy, one way, estimate. Tap a connection for miles by cabin.

7 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.