Are there nonstop flights from Calgary (YYC) to Panama City (PTY)?

Yes. WestJet fly this route. Flight time is about 7h 8m.

What is the fastest connection from Calgary (YYC) to Panama City (PTY)?

via Cancún ≈ 7h 39m, via Houston ≈ 7h 41m, via Denver ≈ 7h 41m (estimated flying time, excluding layovers).

from 30,000 ANA miles (economy, one way, based on the published award charts).

Calgary International Airport (YYC) to Tocumen International Airport (PTY)・5,642 km

Nonstop flights available (1 airline). Flight time about 7h 8m. Nonstop return flights also operate.

With milesANA 30,000 miles+ (via IAH)Economy, one way, estimate. Tap a connection for miles by cabin.

27 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.