Are there nonstop flights from Ottawa (YOW) to Buffalo (BUF)?

No. The fastest connection is via Newark, about 2h 9m of total flying time.

What is the fastest connection from Ottawa (YOW) to Buffalo (BUF)?

via Newark ≈ 2h 9m, via Boston ≈ 2h 20m, via Washington ≈ 2h 23m (estimated flying time, excluding layovers).

Ottawa Macdonald-Cartier International Airport (YOW) to Buffalo Niagara International Airport (BUF)・360 km

No nonstop flights. The fastest connection is via Newark (EWR), about 2h 9m of flying time (layover not included).

None.

4 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.