Are there nonstop flights from Wrocław (WRO) to Madrid (MAD)?

Yes. Ryanair, Wizz Air fly this route. Flight time is about 2h 49m.

What is the fastest connection from Wrocław (WRO) to Madrid (MAD)?

via Zurich ≈ 3h 18m, via Basel / Mulhouse ≈ 3h 19m, via Munich ≈ 3h 20m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Copernicus Wrocław Airport (WRO) to Adolfo Suárez Madrid–Barajas Airport (MAD)・1,965 km

Nonstop flights available (2 airlines). Flight time about 2h 49m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via ZRH)Economy, one way, estimate. Tap a connection for miles by cabin.

56 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.