Are there nonstop flights from Vilnius (VNO) to Rome (FCO)?

Yes. Ryanair fly this route. Flight time is about 2h 31m.

What is the fastest connection from Vilnius (VNO) to Rome (FCO)?

via Kraków ≈ 3h 1m, via Warsaw ≈ 3h 2m, via Vienna ≈ 3h 2m (estimated flying time, excluding layovers).

from 15,000 ANA miles, from 15,000 JAL miles (economy, one way, based on the published award charts).

Vilnius International Airport (VNO) to Rome–Fiumicino Leonardo da Vinci International Airport (FCO)・1,717 km

Nonstop flights available (1 airline). Flight time about 2h 31m. Nonstop return flights also operate.

With milesANA 15,000 miles+ (via WAW)JAL 15,000 miles+ (via HEL)Economy, one way, estimate. Tap a connection for miles by cabin.

46 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.