Are there nonstop flights from Quito (UIO) to Santiago (SCL)?

No. The fastest connection is via Lima, about 5h 28m of total flying time.

What is the fastest connection from Quito (UIO) to Santiago (SCL)?

via Lima ≈ 5h 28m, via Guayaquil ≈ 5h 34m, via Bogota ≈ 6h 50m (estimated flying time, excluding layovers).

from 17,500 ANA miles (economy, one way, based on the published award charts).

Mariscal Sucre International Airport (UIO) to Comodoro Arturo Merino Benítez International Airport (SCL)・3,783 km

No nonstop flights. The fastest connection is via Lima (LIM), about 5h 28m of flying time (layover not included).

With milesANA 17,500 miles+ (via BOG)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

NEWStarting soon: LATAM Airlines Chile

6 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.