Are there nonstop flights from Quito (UIO) to Cuenca (CUE)?

Yes. Avianca Ecuador, LATAM Airlines Ecuador, Aeroregional fly this route. Flight time is about 52m.

What is the fastest connection from Quito (UIO) to Cuenca (CUE)?

via Guayaquil ≈ 1h 29m (estimated flying time, excluding layovers).

Mariscal Sucre International Airport (UIO) to Mariscal Lamar Airport (CUE)・315 km

Nonstop flights available (3 airlines). Flight time about 52m. Nonstop return flights also operate.

1 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.