Are there nonstop flights from Tucson (TUS) to Louisville (SDF)?

No. The fastest connection is via Dallas-Fort Worth, about 3h 55m of total flying time.

What is the fastest connection from Tucson (TUS) to Louisville (SDF)?

via Dallas-Fort Worth ≈ 3h 55m, via Dallas ≈ 3h 55m, via Phoenix ≈ 4h 4m (estimated flying time, excluding layovers).

from 15,000 JAL miles, from 15,000 ANA miles (economy, one way, based on the published award charts).

Tucson International Airport (TUS) to Louisville Muhammad Ali International Airport (SDF)・2,380 km

No nonstop flights. The fastest connection is via Dallas-Fort Worth (DFW), about 3h 55m of flying time (layover not included).

With milesJAL 15,000 miles+ (via DFW)ANA 15,000 miles+ (via DEN)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

13 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.