Are there nonstop flights from São Tomé (TMS) to Bissau (OXB)?

No. The fastest connection is via Lomé, about 4h 20m of total flying time.

What is the fastest connection from São Tomé (TMS) to Bissau (OXB)?

via Lomé ≈ 4h 20m (estimated flying time, excluding layovers).

São Tomé International Airport (TMS) to Osvaldo Vieira International Airport (OXB)・2,781 km

No nonstop flights. The fastest connection is via Lomé (LFW), about 4h 20m of flying time (layover not included).

None.

1 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.