Are there nonstop flights from Syracuse (SYR) to Panama City (PTY)?

No. The fastest connection is via Washington, about 5h 29m of total flying time.

What is the fastest connection from Syracuse (SYR) to Panama City (PTY)?

via Washington ≈ 5h 29m, via Raleigh/Durham ≈ 5h 29m, via Fort Lauderdale ≈ 5h 30m (estimated flying time, excluding layovers).

from 30,000 ANA miles (economy, one way, based on the published award charts).

Syracuse Hancock International Airport (SYR) to Tocumen International Airport (PTY)・3,798 km

No nonstop flights. The fastest connection is via Washington (IAD), about 5h 29m of flying time (layover not included).

With milesANA 30,000 miles+ (via ORD)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

11 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.