Are there nonstop flights from London (STN) to Santander (SDR)?

Yes. Ryanair fly this route. Flight time is about 1h 40m.

What is the fastest connection from London (STN) to Santander (SDR)?

via Dublin ≈ 2h 52m, via Madrid ≈ 2h 55m, via Barcelona ≈ 3h 2m (estimated flying time, excluding layovers).

London Stansted Airport (STN) to Seve Ballesteros-Santander Airport (SDR)・988 km

Nonstop flights available (1 airline). Flight time about 1h 40m. Nonstop return flights also operate.

13 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.