Are there nonstop flights from St Louis (STL) to Madrid (MAD)?

No. The fastest connection is via Montréal, about 9h 22m of total flying time.

What is the fastest connection from St Louis (STL) to Madrid (MAD)?

via Montréal ≈ 9h 22m, via Toronto ≈ 9h 22m, via Boston ≈ 9h 25m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

St. Louis Lambert International Airport (STL) to Adolfo Suárez Madrid–Barajas Airport (MAD)・7,108 km

No nonstop flights. The fastest connection is via Montréal (YUL), about 9h 22m of flying time (layover not included).

With milesANA 27,500 miles+ (via YUL)JAL 37,000 miles+ (via ORD)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

19 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.