Are there nonstop flights from St Louis (STL) to Cape Town (CPT)?

No. The fastest connection is via Atlanta, about 17h 19m of total flying time.

What is the fastest connection from St Louis (STL) to Cape Town (CPT)?

via Atlanta ≈ 17h 19m, via Washington ≈ 17h 20m, via Newark ≈ 17h 28m (estimated flying time, excluding layovers).

from 35,000 ANA miles, from 50,000 JAL miles (economy, one way, based on the published award charts).

St. Louis Lambert International Airport (STL) to Cape Town International Airport (CPT)・13,795 km

No nonstop flights. The fastest connection is via Atlanta (ATL), about 17h 19m of flying time (layover not included).

With milesANA 35,000 miles+ (via EWR)JAL 50,000 miles+ (via LHR)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

5 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.