Are there nonstop flights from Springfield (SPI) to Chicago (ORD)?

Yes. American Eagle (airline brand) fly this route. Flight time is about 50m.

Springfield → Chicago

Abraham Lincoln Capital Airport (SPI) to Chicago O'Hare International Airport (ORD)・280 km

Nonstop flights available (1 airline). Flight time about 50m. Nonstop return flights also operate.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.