Are there nonstop flights from Santa Ana (SNA) to Rome (FCO)?

No. The fastest connection is via Denver, about 13h 6m of total flying time.

What is the fastest connection from Santa Ana (SNA) to Rome (FCO)?

via Denver ≈ 13h 6m, via Minneapolis ≈ 13h 8m, via Calgary ≈ 13h 15m (estimated flying time, excluding layovers).

from 27,500 ANA miles, from 45,000 JAL miles (economy, one way, based on the published award charts).

John Wayne Orange County International Airport (SNA) to Rome–Fiumicino Leonardo da Vinci International Airport (FCO)・10,200 km

No nonstop flights. The fastest connection is via Denver (DEN), about 13h 6m of flying time (layover not included).

With milesANA 27,500 miles+ (via DEN)JAL 45,000 miles+ (via ORD)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

14 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.