Are there nonstop flights from Samos Island (SMI) to Luton (LTN)?

No. The fastest connection is via Munich, about 4h 7m of total flying time.

What is the fastest connection from Samos Island (SMI) to Luton (LTN)?

via Munich ≈ 4h 7m, via Zurich ≈ 4h 7m, via Athens ≈ 4h 10m (estimated flying time, excluding layovers).

Samos Airport (SMI) to London Luton Airport (LTN)・2,643 km

No nonstop flights. The fastest connection is via Munich (MUC), about 4h 7m of flying time (layover not included).

None.

7 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.