Are there nonstop flights from Samos Island (SMI) to Rome (FCO)?

No. The fastest connection is via Athens, about 2h 35m of total flying time.

What is the fastest connection from Samos Island (SMI) to Rome (FCO)?

via Athens ≈ 2h 35m, via Thessaloniki ≈ 2h 37m, via Rhodes ≈ 2h 57m (estimated flying time, excluding layovers).

from 15,000 ANA miles (economy, one way, based on the published award charts).

Samos Airport (SMI) to Rome–Fiumicino Leonardo da Vinci International Airport (FCO)・1,332 km

No nonstop flights. The fastest connection is via Athens (ATH), about 2h 35m of flying time (layover not included).

With milesANA 15,000 miles+ (via ATH)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

9 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.