Are there nonstop flights from Samos Island (SMI) to Newark (EWR)?

No. The fastest connection is via Zurich, about 10h 37m of total flying time.

What is the fastest connection from Samos Island (SMI) to Newark (EWR)?

via Zurich ≈ 10h 37m, via Milan ≈ 10h 37m, via Brussels ≈ 10h 39m (estimated flying time, excluding layovers).

from 27,500 ANA miles (economy, one way, based on the published award charts).

Samos Airport (SMI) to Newark Liberty International Airport (EWR)・8,178 km

No nonstop flights. The fastest connection is via Zurich (ZRH), about 10h 37m of flying time (layover not included).

With milesANA 27,500 miles+ (via BRU)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

8 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.