Are there nonstop flights from Espargos (SID) to Luton (LTN)?

No. The fastest connection is via Porto, about 6h 10m of total flying time.

What is the fastest connection from Espargos (SID) to Luton (LTN)?

via Porto ≈ 6h 10m, via Lisbon ≈ 6h 10m, via Gran Canaria ≈ 6h 11m (estimated flying time, excluding layovers).

Amílcar Cabral International Airport (SID) to London Luton Airport (LTN)・4,384 km

No nonstop flights. The fastest connection is via Porto (OPO), about 6h 10m of flying time (layover not included).

None.

15 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.