Are there nonstop flights from San Francisco (SFO) to Manchester (MHT)?

No. The fastest connection is via Chicago, about 6h 5m of total flying time.

What is the fastest connection from San Francisco (SFO) to Manchester (MHT)?

via Chicago ≈ 6h 5m, via Chicago ≈ 6h 5m, via Philadelphia ≈ 6h 19m (estimated flying time, excluding layovers).

from 23,000 JAL miles (economy, one way, based on the published award charts).

San Francisco International Airport (SFO) to Manchester-Boston Regional Airport (MHT)・4,295 km

No nonstop flights. The fastest connection is via Chicago (ORD), about 6h 5m of flying time (layover not included).

With milesJAL 23,000 miles+ (via CLT)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

12 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.