Are there nonstop flights from San Francisco (SFO) to Medellín (MDE)?

No. The fastest connection is via Panama City, about 7h 55m of total flying time.

What is the fastest connection from San Francisco (SFO) to Medellín (MDE)?

via Panama City ≈ 7h 55m, via Cancún ≈ 7h 59m, via Guatemala City ≈ 8h (estimated flying time, excluding layovers).

from 23,000 JAL miles, from 30,000 ANA miles (economy, one way, based on the published award charts).

San Francisco International Airport (SFO) to Jose Maria Córdova International Airport (MDE)・5,883 km

No nonstop flights. The fastest connection is via Panama City (PTY), about 7h 55m of flying time (layover not included).

With milesJAL 23,000 miles+ (via MIA)ANA 30,000 miles+ (via PTY)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

13 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.