Are there nonstop flights from San Francisco (SFO) to Guatemala City (GUA)?

Yes. Avianca El Salvador fly this route. Flight time is about 5h 16m.

What is the fastest connection from San Francisco (SFO) to Guatemala City (GUA)?

via Los Angeles ≈ 5h 47m, via Mexico City ≈ 5h 49m, via Belize City ≈ 6h 11m (estimated flying time, excluding layovers).

from 23,000 JAL miles, from 30,000 ANA miles (economy, one way, based on the published award charts).

San Francisco International Airport (SFO) to La Aurora International Airport (GUA)・4,048 km

Nonstop flights available (1 airline). Flight time about 5h 16m. Nonstop return flights also operate.

With milesJAL 23,000 miles+ (via LAX)ANA 30,000 miles+ (via LAX)Economy, one way, estimate. Tap a connection for miles by cabin.

18 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.