Are there nonstop flights from San Francisco (SFO) to São Paulo (GRU)?

No. The fastest connection is via Panama City, about 13h 16m of total flying time.

What is the fastest connection from San Francisco (SFO) to São Paulo (GRU)?

via Panama City ≈ 13h 16m, via Los Angeles ≈ 13h 18m, via Mexico City ≈ 13h 19m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 40,000 JAL miles (economy, one way, based on the published award charts).

San Francisco International Airport (SFO) to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU)・10,427 km

No nonstop flights. The fastest connection is via Panama City (PTY), about 13h 16m of flying time (layover not included).

With milesANA 30,000 miles+ (via PTY)JAL 40,000 miles+ (via JFK)Economy, one way, estimate. Tap a connection for miles by cabin.

None.

26 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.