Are there nonstop flights from Southend-on-Sea (SEN) to Panama City (PTY)?

No. The fastest connection is via Paris, about 11h 33m of total flying time.

What is the fastest connection from Southend-on-Sea (SEN) to Panama City (PTY)?

via Paris ≈ 11h 33m, via Amsterdam ≈ 11h 43m (estimated flying time, excluding layovers).

London Southend Airport (SEN) to Tocumen International Airport (PTY)・8,534 km

No nonstop flights. The fastest connection is via Paris (CDG), about 11h 33m of flying time (layover not included).

None.

2 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.