Are there nonstop flights from Southend-on-Sea (SEN) to Palermo (PMO)?

No. The fastest connection is via Geneva, about 3h 5m of total flying time.

What is the fastest connection from Southend-on-Sea (SEN) to Palermo (PMO)?

via Geneva ≈ 3h 5m, via Paris ≈ 3h 6m, via Pisa ≈ 3h 6m (estimated flying time, excluding layovers).

London Southend Airport (SEN) to Falcone–Borsellino Airport (PMO)・1,776 km

No nonstop flights. The fastest connection is via Geneva (GVA), about 3h 5m of flying time (layover not included).

None.

11 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.