Are there nonstop flights from Santiago (SCL) to Osorno (ZOS)?

Yes. LATAM Airlines Chile, Sky Airline fly this route. Flight time is about 1h 28m.

Santiago → Osorno

Comodoro Arturo Merino Benítez International Airport (SCL) to Cañal Bajo Carlos Hott Siebert Airport (ZOS)・828 km

Nonstop flights available (2 airlines). Flight time about 1h 28m. Nonstop return flights also operate.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.