Are there nonstop flights from Santiago (SCL) to Cancún (CUN)?

Yes. LATAM Airlines Chile fly this route. Flight time is about 7h 54m.

What is the fastest connection from Santiago (SCL) to Cancún (CUN)?

via Lima ≈ 8h 24m, via Panama City ≈ 8h 29m, via Medellín ≈ 8h 38m (estimated flying time, excluding layovers).

from 30,000 ANA miles, from 37,000 JAL miles (economy, one way, based on the published award charts).

Comodoro Arturo Merino Benítez International Airport (SCL) to Cancún International Airport (CUN)・6,289 km

Nonstop flights available (1 airline). Flight time about 7h 54m. Nonstop return flights also operate.

With milesANA 30,000 miles+ (via PTY)JAL 37,000 miles+ (via MIA)Economy, one way, estimate. Tap a connection for miles by cabin.

16 one-stop options, sorted by estimated flying time. Tap one to see the airlines on each leg and booking links.

Times are estimated from distance. Check schedules, frequency and availability with the airline or a booking site.